Question 1

The nurse explains to a client receiving chemotherapy that leucovorin (Wellcovorin) is used in conjunction with methotrexate to do which of the following?

Accepted Answer

A)   Treat hyperkeratosis
B)   Diminish the risk of bony metastasis
C)   Act to increase the cancer cell kill
D)   Protect normal cells from toxic effects of the drugE) A) and C)
F) A) and B)

Question 2

The nurse plans to assess the client receiving dacarbazine (DTIC-Dome) for which of the following adverse drug effects?

Accepted Answer

A)   Nausea and vomiting
B)   Stomatitis
C)   Hemorrhagic cystitis
D)   Chest painE) All of the above
F) A) and B)

Question 3

The nurse would most carefully assess a client who received fludarabine (Fludara) for evidence of myelosuppression at which of the following timeframes after infusion?

Accepted Answer

A)   1 to 3 days
B)   5 to 7 days
C)   10 to 14 days
D)   21 to 28 daysE) None of the above
F) B) and C) C

Question 4

The nurse notes that a client receiving which of the following chemotherapy drugs is being treated with an agent that is a nitrosourea?

Accepted Answer

A)   Busulfan (Myleran) 
B)   Floxuridine (FUDR) 
C)   Cisplatin (Platinol) 
D)   Carmustine (BiCNU) E) A) and B)
F) A) and C)

Question 5

The client with cancer asks the nurse about the newly ordered drug tamoxifen (Nolvadex) .The nurse explains that this drug is which of the following types of drugs?

Accepted Answer

A)   Synthetic steroidal chemotherapeutic agent
B)   Antitestosterone agent
C)   Antiestrogen agent
D)   Vinca alkaloidE) All of the above
F) C) and D) C

Question 6

After noting a chemotherapy order for the drug lomustine (CeeNU) in a client with cancer,the nurse concludes that which of the following is most likely the affected site?

Accepted Answer

A)   Breast
B)   Ovary
C)   Brain
D)   StomachE) A) and D)
F) B) and D)

Question 7

Fluorouracil is ordered as an adjunct therapy to surgery.The nurse recalls that this drug is classified as which of the following types of chemotherapy drugs?

Accepted Answer

A)   Antimetabolite agent
B)   Antibiotic antitumor agent
C)   Alkylating agent
D)   Hormonal antitumor agentE) B) and C)
F) All of the above

Question 8

What instructions should the nurse give to the client who is receiving fluorouracil therapy?

Accepted Answer

A)   Take the medication orally
B)   Get routine immunizations to prevent influenza and pneumonia
C)   Refrain from being immunized with live virus vaccines
D)   Immunize only family membersE) B) and C)
F) A) and D)

Question 9

The nurse overhears a client who has cancer tell the family that the physician will order an antitumor antibiotic.The nurse suspects that which of the following agents may be used?

Accepted Answer

A)   Thiotepa (Thioplex) 
B)   Gemcitabine (Gemzar) 
C)   Mitomycin (Mutamycin) 
D)   Paclitaxel (Onxol,Taxol) E) A) and C)
F) A) and B) C

Question 10

The nurse assesses that a client who is receiving cisplatin (Platinol) as chemotherapy is at increased risk for which of the following conditions?

Accepted Answer

A)   Hyperreflexia
B)   Tinnitus
C)   Polyuria
D)   LeukocytosisE) None of the above
F) A) and B)

Question 11

If extravasation of intravenous fluorouracil occurs,the most appropriate nursing intervention would be to stop the infusion and

Accepted Answer

A)   apply warm compresses.
B)   give 25% hydrocortisone intramuscularly.
C)   apply cold compresses.
D)   give 20% lidocaine intravenously.E) B) and C)
F) A) and D)

Question 12

A client with cancer has an order for chemotherapy with asparaginase (Elspar) .The nurse suspects that the client has which of the following types of cancer?

Accepted Answer

A)   Neuroblastoma
B)   Cancer of the colon
C)   Acute lymphocytic leukemia
D)   Prostate cancerE) B) and C)
F) None of the above

Question 13

The nurse would assess the client receiving doxorubicin (Adriamycin) for which of the following signs of toxicity?

Accepted Answer

A)   Ringing in the ears
B)   Heart failure
C)   Dyspnea
D)   ParesthesiasE) C) and D)
F) All of the above

Question 14

The nurse understands that a client with which of the following conditions could not be treated effectively with cyclophosphamide (Cytoxan) ?

Accepted Answer

A)   Acute leukemia
B)   Drug-resistant nephrotic syndrome
C)   Polycythemia vera
D)   Mycosis fungoidesE) A) and B)
F) None of the above

Question 15

The nurse expects that a client will be receiving which of the following drugs after hearing that a client with cancer will be treated with a mitotic inhibitor?

Accepted Answer

A)   Mechlorethamine (Mustargen) 
B)   Fluorouracil (Adrucil) 
C)   Epirubicin (Ellence) 
D)   Vincristine (Oncovin) E) A) and B)
F) C) and D)

Question 16

The nurse suspects that the client has cancer in which of the following sites after reading an order for paclitaxel (Taxol) ?

Accepted Answer

A)   Breast
B)   Colon
C)   Pancreas
D)   BoneE) All of the above
F) B) and D)

Question 17

The nurse notes that a client has an order for chemotherapy with flutamide (Eulexin) and also has an order for leuprolide (Lupron) .The nurse suspects that the client has which type of metastatic cancer?

Accepted Answer

A)   Testicular
B)   Prostate
C)   Brain
D)   BoneE) A) and C)
F) C) and D)

Question 18

The nurse who is assessing a client receiving cisplatin (Platinol) would not be concerned about the development of which of the following adverse effects from this chemotherapeutic agent?

Accepted Answer

A)   Nephrotoxicity
B)   Neurotoxicity
C)   Ototoxicity
D)   Pulmonary toxicityE) A) and C)
F) None of the above

Question 19

The nurse who reads a physician progress note for a client with cancer would expect which of the following drugs to be used if the plan is to use an alkylating agent?

Accepted Answer

A)   Busulfan (Myleran) 
B)   Mercaptopurine (Purinethol) 
C)   Bleomycin (Blenoxane) 
D)   Docetaxel (Taxotere) E) A) and D)
F) B) and C)

Question 20

The nurse would question an order for cyclophosphamide (Cytoxan) for a client with which of the following conditions?

Accepted Answer

A)   Chronic leukemia
B)   Carcinoma of the breast
C)   Multiple myeloma
D)   Herpes zoster infectionE) A) and B)
F) A) and C)

Exam 56: Antineoplastic Chemotherapy Agents

The nurse explains to a client receiving chemotherapy that leucovorin (Wellcovorin) is used in conjunction with methotrexate to do which of the following?

Correct AnswerverifiedShow Answer

The nurse plans to assess the client receiving dacarbazine (DTIC-Dome) for which of the following adverse drug effects?

Correct AnswerverifiedShow Answer

The nurse would most carefully assess a client who received fludarabine (Fludara) for evidence of myelosuppression at which of the following timeframes after infusion?

Correct AnswerverifiedC

The nurse notes that a client receiving which of the following chemotherapy drugs is being treated with an agent that is a nitrosourea?

Correct AnswerverifiedShow Answer

The client with cancer asks the nurse about the newly ordered drug tamoxifen (Nolvadex) .The nurse explains that this drug is which of the following types of drugs?

Correct AnswerverifiedC

After noting a chemotherapy order for the drug lomustine (CeeNU) in a client with cancer,the nurse concludes that which of the following is most likely the affected site?

Correct AnswerverifiedShow Answer

Fluorouracil is ordered as an adjunct therapy to surgery.The nurse recalls that this drug is classified as which of the following types of chemotherapy drugs?

Correct AnswerverifiedShow Answer

What instructions should the nurse give to the client who is receiving fluorouracil therapy?

Correct AnswerverifiedShow Answer

The nurse overhears a client who has cancer tell the family that the physician will order an antitumor antibiotic.The nurse suspects that which of the following agents may be used?

Correct AnswerverifiedC

The nurse assesses that a client who is receiving cisplatin (Platinol) as chemotherapy is at increased risk for which of the following conditions?

Correct AnswerverifiedShow Answer

If extravasation of intravenous fluorouracil occurs,the most appropriate nursing intervention would be to stop the infusion and

Correct AnswerverifiedShow Answer

A client with cancer has an order for chemotherapy with asparaginase (Elspar) .The nurse suspects that the client has which of the following types of cancer?

Correct AnswerverifiedShow Answer

The nurse would assess the client receiving doxorubicin (Adriamycin) for which of the following signs of toxicity?

Correct AnswerverifiedShow Answer

The nurse understands that a client with which of the following conditions could not be treated effectively with cyclophosphamide (Cytoxan) ?

Correct AnswerverifiedShow Answer

The nurse expects that a client will be receiving which of the following drugs after hearing that a client with cancer will be treated with a mitotic inhibitor?

Correct AnswerverifiedShow Answer

The nurse suspects that the client has cancer in which of the following sites after reading an order for paclitaxel (Taxol) ?

Correct AnswerverifiedShow Answer

The nurse notes that a client has an order for chemotherapy with flutamide (Eulexin) and also has an order for leuprolide (Lupron) .The nurse suspects that the client has which type of metastatic cancer?

Correct AnswerverifiedShow Answer

The nurse who is assessing a client receiving cisplatin (Platinol) would not be concerned about the development of which of the following adverse effects from this chemotherapeutic agent?

Correct AnswerverifiedShow Answer

The nurse who reads a physician progress note for a client with cancer would expect which of the following drugs to be used if the plan is to use an alkylating agent?

Correct AnswerverifiedShow Answer

The nurse would question an order for cyclophosphamide (Cytoxan) for a client with which of the following conditions?

Correct AnswerverifiedShow Answer

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