Question 1

What groups are at risk for graft-versus-host disease (GVHD)  as a result of transfusion?

Accepted Answer

A)   Polycythemia vera patients undergoing a therapeutic phlebotomy
B)   Fetuses receiving an intrauterine transfusion
C)   Patients receiving a directed donation from a first-degree relative
D)   Options B and CE) A) and B)
F) All of the above

Question 2

Which of the following should be collected immediately from a patient exhibiting signs of a septic reaction to blood products?

Accepted Answer

A)   DAT
B)   Complete blood count (CB
C)  
C)   Urine sample
D)   Blood culturesE) B) and C)
F) A) and B)

Question 3

What is the pathophysiological cause surrounding anaphylactic and anaphylactoid reactions?

Accepted Answer

A)   Antibody in patient serum is detected 3 to 7 days after transfusion, reacting with donor red blood cells
B)   Donor plasma has reagins (IgE or Ig
A)   that combine with allergens in patient plasma
C)   A patient who is deficient in IgE develops IgE antibodies via sensitization from transfusion or pregnancy
D)   A patient who is deficient in IgA develops IgA antibodies via sensitization from transfusion or pregnancyE) All of the above
F) B) and D)

Question 4

A patient transfused with 2 units of packed red blood cells demonstrated signs of a transfusion reaction just before the second unit was completely infused. Hypotension, fever, and back pain are the immediate symptoms. Blood work reveals a 3% drop in hematocrit and prolonged PT. What therapy is given to correct the PT?

Accepted Answer

A)   FFP
B)   Dopamine
C)   Platelet concentrates
D)   MannitolE) A) and B)
F) B) and D)

Question 5

How could a potential alloimmunizaton due to anti-K be prevented?

Accepted Answer

A)   Matching of donor and recipient red blood cell phenotype
B)   Use of third-generation bedside leukocyte filters
C)   Use of washed red blood cells
D)   Use of apheresed plateletsE) C) and D)
F) None of the above

Question 6

Circulatory overload is cause by which of the following?

Accepted Answer

A)   Excessive transfused fluid
B)   Rapid rate of infusion
C)   decreased cardiac capacity
D)   All of theseE) B) and C)
F) A) and C)

Question 7

A 35-year-old woman was transfused with 1 unit of packed red blood cells. The nurse monitoring the transfusion noticed hives on the patient's arm and an increase in body temperature. What is the choice of treatment for this patient?

Accepted Answer

A)   Leukopoor blood products
B)   Antihistamines
C)   Premedication with aspirin
D)   None of the aboveE) A) and B)
F) All of the above

Question 8

Immediate transfusion reaction procedures consist of all of the following except:

Accepted Answer

A)   clerical check.
B)   DAT.
C)   serum haptoglobin.
D)   visual check.E) None of the above
F) All of the above

Question 9

Which of the following best describes a transfusion reaction?

Accepted Answer

A)   An urticarial response to blood products occurring 1 to 2 hours after infusion
B)   A physiologic response to a blood product transfused 5 to 10 days before host symptoms
C)   Any unfavorable transfusion-related event occurring in a patient during or after transfusion of blood components
D)   None of the aboveE) A) and C)
F) A) and D)

Question 10

What should be done in the transfusion process when the patient temperature spikes from 37.5°C to 38.5°C within 30 minutes of transfusion?

Accepted Answer

A)   Continue the transfusion.
B)   Stop the transfusion and keep the intravenous line open.
C)   Treat with diphenhydramine (Benadryl) .
D)   Affix a leukocyte filter to transfusion line.E) B) and C)
F) All of the above

Question 11

What is the physiologic mechanism of histamine?

Accepted Answer

A)   Histamine is released when the allergen-reagin complex attaches to the surface of basophils, increasing vascular dilation and permeability
B)   Histamine is released when the allergen-reagin complex attaches to the surface of tissue mast cells, increasing vascular dilation and permeability
C)   Histamine is released when the allergen-reagin complex attaches to the surface of eosinophils, increasing vascular dilation and permeability
D)   Histamine is released when the allergen-reagin complex attaches to the surface of tissue mast cells, decreasing vascular dilation and permeabilityE) None of the above
F) A) and C)

Question 12

Which mechanism may play a role in fever development in an FNHTR?

Accepted Answer

A)   Release of pyrogens from transfused white blood cells
B)   The production of interleukin-6 by the complement system
C)   Synthesis of prostaglandins (PGE±)  in hypothalamic cells by interleukin-6
D)   None of the aboveE) B) and C)
F) A) and B)

Question 13

A negative direct antiglobulin test (DAT)  is found in all of the following transfusion reactions except:

Accepted Answer

A)   Acute nonimmune hemolytic transfusion reaction
B)   Febrile nonhemolytic transfusion reaction
C)   Acute immune hemolytic transfusion reaction
D)   Transfusion-associated sepsisE) All of the above
F) A) and B)

Question 14

Which of the following products may lead to sepsis in a patient when contaminated with Escherichia coli?

Accepted Answer

A)   Packed red blood cells
B)   Normal saline
C)   Platelets
D)   All of the aboveE) A) and B)
F) A) and C)

Question 15

All of the following are diseases that can mimic a transfusion reaction except:

Accepted Answer

A)   AML.
B)   hemoglobin C disease.
C)   G6PD deficiency.
D)   PNH.E) B) and D)
F) A) and B)

Question 16

What is the most common preventable error occurring among the nursing and medical staff that results in a transfusion-related death?

Accepted Answer

A)   Alloantibody misidentified
B)   Improper patient identification
C)   Specimen mislabeled
D)   Incorrect crossmatch procedureE) A) and D)
F) A) and C)

Question 17

Persons with a documented history of anaphylactic reactions should be transfused with blood products.

Accepted Answer

A)   IgE-deficient
B)   leukodepleted
C)   washed
D)   irradiatedE) All of the above
F) A) and D)

Question 18

What is the most frequent cause of circulatory overload?

Accepted Answer

A)   Transfusion of a unit at too slow a rate
B)   Massive transfusion of blood components
C)   Transfusion of a unit at too fast a rate
D)   Transfusion of a partially deglycerolized unitE) B) and C)
F) C) and D)

Question 19

The plasma level of unconjugated bilirubin is elevated in:

Accepted Answer

A)   intravascular hemolysis.
B)   extravascular hemolysis.
C)   intravascular and extravascular hemolysis.
D)   none of the above.E) A) and B)
F) All of the above

Question 20

All of the following are symptoms of an allergic reaction except:

Accepted Answer

A)   pruritus.
B)   local erythema.
C)   anemia.
D)   hives.E) All of the above
F) None of the above

Exam 17: Adverse Effects of Blood Transfusion

All of the following are symptoms of an allergic reaction except:

Correct Answer
verified

Correct Answer
verified

All of the following are diseases that can mimic a transfusion reaction except:

Correct Answer
verified

Persons with a documented history of anaphylactic reactions should be transfused with blood products.

Correct Answer
verified

What is the most frequent cause of circulatory overload?

Correct Answer
verified

What is the most common preventable error occurring among the nursing and medical staff that results in a transfusion-related death?

Correct Answer
verified

Which of the following products may lead to sepsis in a patient when contaminated with Escherichia coli?

Correct Answer
verified

What is the physiologic mechanism of histamine?

Correct Answer
verified

Circulatory overload is cause by which of the following?

Correct Answer
verified

How could a potential alloimmunizaton due to anti-K be prevented?

Correct Answer
verified

Which of the following should be collected immediately from a patient exhibiting signs of a septic reaction to blood products?

Correct Answer
verified

The plasma level of unconjugated bilirubin is elevated in:

Correct Answer
verified

Which mechanism may play a role in fever development in an FNHTR?

Correct Answer
verified

A negative direct antiglobulin test (DAT) is found in all of the following transfusion reactions except:

Correct Answer
verified

A 35-year-old woman was transfused with 1 unit of packed red blood cells. The nurse monitoring the transfusion noticed hives on the patient's arm and an increase in body temperature. What is the choice of treatment for this patient?

Correct Answer
verified

What should be done in the transfusion process when the patient temperature spikes from 37.5°C to 38.5°C within 30 minutes of transfusion?

Correct Answer
verified

Which of the following best describes a transfusion reaction?

Correct Answer
verified

What groups are at risk for graft-versus-host disease (GVHD) as a result of transfusion?

Correct Answer
verified

What is the pathophysiological cause surrounding anaphylactic and anaphylactoid reactions?

Correct Answer
verified

Immediate transfusion reaction procedures consist of all of the following except:

Correct Answer
verified

Exam 17: Adverse Effects of Blood Transfusion

All of the following are symptoms of an allergic reaction except:

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

All of the following are diseases that can mimic a transfusion reaction except:

Correct AnswerverifiedShow Answer

Persons with a documented history of anaphylactic reactions should be transfused with blood products.

Correct AnswerverifiedShow Answer

What is the most frequent cause of circulatory overload?

Correct AnswerverifiedShow Answer

What is the most common preventable error occurring among the nursing and medical staff that results in a transfusion-related death?

Correct AnswerverifiedShow Answer

Which of the following products may lead to sepsis in a patient when contaminated with Escherichia coli?

Correct AnswerverifiedShow Answer

What is the physiologic mechanism of histamine?

Correct AnswerverifiedShow Answer

Circulatory overload is cause by which of the following?

Correct AnswerverifiedShow Answer

How could a potential alloimmunizaton due to anti-K be prevented?

Correct AnswerverifiedShow Answer

Which of the following should be collected immediately from a patient exhibiting signs of a septic reaction to blood products?

Correct AnswerverifiedShow Answer

The plasma level of unconjugated bilirubin is elevated in:

Correct AnswerverifiedShow Answer

Which mechanism may play a role in fever development in an FNHTR?

Correct AnswerverifiedShow Answer

A negative direct antiglobulin test (DAT) is found in all of the following transfusion reactions except:

Correct AnswerverifiedShow Answer

A 35-year-old woman was transfused with 1 unit of packed red blood cells. The nurse monitoring the transfusion noticed hives on the patient's arm and an increase in body temperature. What is the choice of treatment for this patient?

Correct AnswerverifiedShow Answer

What should be done in the transfusion process when the patient temperature spikes from 37.5°C to 38.5°C within 30 minutes of transfusion?

Correct AnswerverifiedShow Answer

Which of the following best describes a transfusion reaction?

Correct AnswerverifiedShow Answer

What groups are at risk for graft-versus-host disease (GVHD) as a result of transfusion?

Correct AnswerverifiedShow Answer

What is the pathophysiological cause surrounding anaphylactic and anaphylactoid reactions?

Correct AnswerverifiedShow Answer

Immediate transfusion reaction procedures consist of all of the following except:

Correct AnswerverifiedShow Answer

Correct Answer
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Correct Answer
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Correct Answer
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