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What condition(s) must exist for a solute to be passively reabsorbed from the renal tubules?


A) The solute must be able to permeate the membrane of the capillary endothelial cells, and the solute must be in greater concentration in the plasma than tubule fluid.
B) The solute must be able to permeate the membrane of the tubule epithelial cells and capillary endothelial cells. Its concentration is irrelevant.
C) The solute must be able to permeate the membrane of the capillary endothelial cells, and the solute must be in greater concentration in the tubule fluid than plasma.
D) The solute must be able to permeate the membrane of the tubule epithelial cells, and the solute must be in greater concentration in the plasma than tubule fluid.
E) The solute must be able to permeate the membrane of the tubule epithelial cells, and the solute must be in greater concentration in the tubule fluid than plasma.

F) D) and E)
G) A) and E)

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Diabetic nephropathy is caused by hyperglycemia.

A) True
B) False

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Substances can enter the renal tubules by what renal processes?


A) filtration only
B) reabsorption only
C) secretion only
D) both filtration and secretion
E) both reabsorption and secretion

F) C) and D)
G) A) and D)

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Within the kidneys, what membrane has microvilli?


A) apical membrane of renal tubule epithelial cells
B) apical membrane of vasa recta endothelial cells
C) glomerulus
D) basolateral membrane of peritubular capillary endothelial cells
E) basolateral membrane of renal tubule epithelial cells

F) None of the above
G) C) and D)

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Stretching of the bladder reflexively causes all of the following EXCEPT


A) excitation of sympathetic neurons, causing the internal urethral sphincter to relax.
B) inhibition of somatic neurons to the external urethral sphincter, causing the sphincter to open.
C) micturition.
D) excitation of parasympathetic neurons, causing the detrusor muscles to contract.
E) opening of the urethral sphincters.

F) B) and E)
G) B) and D)

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If the amount of solute excreted per minute is greater than the filtered load, then the NET effect on the solute is


A) secretion into the renal tubules.
B) an absence of secretion in the renal tubules.
C) reabsorption from the renal tubules.
D) a combination of reabsorption and secretion in the renal tubules.
E) an absence of reabsorption in the renal tubules.

F) B) and E)
G) C) and D)

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A decrease in mean arterial pressure will act exclusively in an extrinsic manner to affect glomerular filtration rate.

A) True
B) False

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If solute B moves passively across the basolateral membrane and is actively transported out of the epithelial cell across the apical membrane, then B is (reabsorbed / secreted) across this epithelium.

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Changes in mean arterial pressure have the potential to alter glomerular filtration rate by directly altering which of the following?


A) glomerular oncotic pressure
B) Bowman's capsule oncotic pressure
C) Bowman's capsule hydrostatic pressure
D) efferent arteriole resistance
E) glomerular capillary hydrostatic pressure

F) B) and C)
G) A) and B)

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If solute C moves passively across the basolateral membrane and is actively transported into the epithelial cell across the apical membrane, then C is (reabsorbed / secreted) across this epithelium.

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Substances that are reabsorbed from the proximal tubule enter which blood vessel?


A) glomerulus
B) vasa recta
C) peritubular capillary
D) efferent arteriole
E) afferent arteriole

F) C) and D)
G) B) and D)

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Over what range of mean arterial pressure does glomerular filtration rate remain stable due to intrinsic regulation?


A) 80 -100 mm Hg
B) 50 -150 mm Hg
C) 80 -180 mm Hg
D) 70 -110 mm Hg
E) 80 -120 mm Hg

F) A) and D)
G) C) and E)

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The vasa recta are in series with the glomerulus.

A) True
B) False

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The connecting tubules join the distal tubule with the collecting ducts.

A) True
B) False

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Which of the following pressures across the glomerular capillaries approaches zero?


A) glomerular oncotic pressure
B) Bowman's capsule oncotic pressure
C) glomerular filtration pressure
D) Bowman's capsule hydrostatic pressure
E) glomerular capillary hydrostatic pressure

F) C) and D)
G) All of the above

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What is the process whereby molecules are selectively transported from the peritubular fluid to the lumen of the renal tubules?


A) reabsorption
B) secretion
C) glomerular filtration
D) absorption
E) excretion

F) B) and E)
G) A) and D)

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Where does blood leaving the glomerulus go next?


A) afferent arteriole
B) Bowman's capsule
C) efferent arteriole
D) peritubular capillary
E) vasa recta

F) B) and C)
G) D) and E)

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What are the three components of the loop of Henle?


A) proximal tubule, loop, and the distal tubule
B) descending limb, thin ascending limb, and thick ascending limb
C) thick descending limb, thin descending limb, and thick ascending limb
D) descending limb, ascending limb, and the bend
E) descending limb, ascending limb, and the vasa recta

F) A) and E)
G) A) and D)

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The reabsorption of sodium and water occurs in a relatively unregulated manner in the proximal tubules.

A) True
B) False

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The primary function of the kidneys involves regulating the__________ and the__________of plasma and interstitial fluid.


A) pressure : volume
B) composition : osmolarity
C) volume : composition
D) temperature : composition
E) volume : temperature

F) D) and E)
G) A) and B)

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