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The magnitude of response at the target cell depends on both the concentration of hormone and the concentration of receptor.

A) True
B) False

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Which of the following correctly describes a pathway for secretion of a hormone under the control of tropic hormones?


A) TRH stimulates TSH release, which stimulates thymosin release.
B) CRH stimulates ACTH release, which stimulates somatomedin release.
C) PRH stimulates PH release, which stimulates prolactin release.
D) GnRH stimulates PH release, which stimulates prolactin release.
E) GHRH stimulates GH release, which stimulates insulin- like growth factor release.

F) A) and D)
G) A) and E)

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What is another name for the posterior lobe of the pituitary gland?


A) paraventricular nucleus
B) neurohypophysis
C) adenohypophysis
D) melanocyte
E) pineal gland

F) A) and B)
G) B) and D)

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Acromegaly is caused by a(n)


A) cortisol deficiency.
B) decrease of insulin- like growth factors.
C) decrease in growth hormone in adults.
D) thyroid deficiency.
E) increase in growth hormone in adults.

F) A) and E)
G) C) and E)

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Which of the following produces the hormone calcitonin?


A) posterior pituitary
B) pancreas
C) adrenal medulla
D) thyroid gland
E) adrenal cortex

F) C) and E)
G) A) and B)

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Which of the following is a CORRECT example of long- loop negative feedback?


A) GH stimulates the release of GHIH.
B) TSH inhibits the release of TRH.
C) TSH stimulates the release of TRH.
D) Glucocorticoids inhibit the release of CRH.
E) FSH inhibits the release of GnRH.

F) A) and E)
G) A) and D)

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Which of the following hormones regulates plasma calcium levels?


A) calcitonin only
B) calcitrol only
C) parathyroid hormone only
D) both calcitonin, and oxytocin
E) calcitonin, calcitrol, and parathyroid hormone

F) A) and D)
G) B) and E)

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Which hormone's release is governed by GnRH?


A) thyroid hormone
B) cortisol
C) glucagon
D) insulin- like growth factors
E) sex hormones

F) D) and E)
G) A) and B)

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A releasing hormone is a type of tropic hormone.

A) True
B) False

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Growth hormone has direct action on target cells throughout the body.

A) True
B) False

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Secretion of hormones from the anterior pituitary is stimulated by released from the .


A) releasing hormones : thalamus
B) oxytocin : hypothalamus
C) stimulating hormones : posterior pituitary
D) tropic hormones : hypothalamus
E) neurotransmitters : hypothalamus

F) B) and D)
G) B) and E)

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What hormone, released by the posterior pituitary, functions in uterine contraction and milk letdown in the breast?


A) antidiuretic hormone
B) vasopressin
C) somatomedin
D) oxytocin
E) prolactin

F) D) and E)
G) B) and C)

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Which of the following hormones is NOT released from the adrenal gland?


A) adrenocorticotropic hormone
B) cortisol
C) androgens
D) aldosterone
E) epinephrine

F) C) and D)
G) A) and B)

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Which of the following tropic hormones is also known as the catecholamine, dopamine?


A) growth hormone
B) luteinizing hormone
C) prolactin inhibiting hormone
D) growth hormone inhibiting hormone
E) prolactin releasing hormone

F) A) and C)
G) A) and B)

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Which of the following endocrine organs essentially secretes hormones from neurons?


A) gonads
B) thymus
C) adrenal cortex
D) pancreas
E) hypothalamus

F) A) and D)
G) C) and D)

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A hormone is when a second hormone is required for the first hormone to have any activity.


A) additive
B) submissive
C) synergistic
D) tropic
E) permissive

F) C) and D)
G) A) and D)

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The mechanism of insulin catabolism in target cells is best described as degradation by


A) peroxisomal enzymes.
B) lysosomes following receptor- mediated endocytosis.
C) insulin- degrading enzyme following receptor- mediated endocytosis.
D) proteases in the extracellular fluid.
E) mitochondrial enzymes following receptor- mediated endocytosis.

F) B) and E)
G) C) and D)

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Which of the following changes in plasma levels would be observed in a primary hyposecretion of cortisol?


A) decreased CRH, decreased ACTH, and decreased cortisol
B) decreased CRH, decreased ACTH, and increased cortisol
C) increased CRH, increased ACTH, and decreased cortisol
D) increased CRH, increased ACTH, and increased cortisol
E) increased CRH, decreased ACTH, and decreased cortisol

F) C) and D)
G) A) and E)

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What are hormones that regulate the release of other hormones?


A) stimulatory hormones
B) release regulating hormones
C) secondary hormones
D) primary hormones
E) tropic hormones

F) C) and D)
G) None of the above

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The concentration of free hormone in the blood depends on all of the following EXCEPT the


A) rate of hormone secretion.
B) amount of hormone temporarily stored in adipose tissue.
C) amount of hormone transported bound to carrier proteins.
D) rate of receptor downregulation.
E) rate at which the hormone is metabolized.

F) B) and E)
G) C) and D)

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