Question 1

Chromosomes that are genetically the same, but have different banding patterns using Hoechst 33258
and Giemsa stains, are called giemequin chromosomes.

Accepted Answer

A) True 
 B)False  False

Question 2

A incomplete transposon contains all of the information necessary to conduct transposition.

Accepted Answer

A) True 
 B)False

Question 3

In the Perry-Wolff experiments with harlequin chromosomes, colcemid was applied to the cells following labeling with BrdU for what reason?

Accepted Answer

A)   To enhance the rate of recombination between chromatids
B)   To reduce the rate of recombination between chromatids
C)   To separate the chromosomes
D)   As a stain
E)   To stop the cells from completing mitosisF) A) and C)
G) B) and C)

Question 4

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Accepted Answer

A)   A nick in only one strand of the DNA
B)   The double-stranded break model
C)   DNA gap repair synthesis
D)   Heteroduplex formationE) A) and B)
F) A) and C)

Question 5

Which of the following is technically not part of the genetic information of a transposable element?

Accepted Answer

A)   Long-terminal repeats
B)   Inverted repeats
C)   Direct repeats
D)   Transposase
E)   All of the answers are correctF) A) and B)
G) B) and D)

Question 6

Transposable elements in bacteria are commonly called insertion sequences.

Accepted Answer

A) True 
 B)False  True

Question 7

The process of recombination occurs during metaphase I of meiosis.

Accepted Answer

A) True 
 B)False

Question 8

Bacteriophage l inserts into a bacterial chromosome using which of the following?

Accepted Answer

A)   Nucleotide excision repair
B)   Endonuclease activity
C)   Site-specific recombination
D)   DNA gap repair
E)   None of the answers are correctF) All of the above
G) D) and E)

Question 9

Which of the following domain types is unique to the heavy chain of the polypeptide?

Accepted Answer

A)   V
B)   D
C)   J
D)   C
E)   None of the answers are correctF) C) and E)
G) A) and D)

Question 10

Which of the following is an example of a transposable element?

Accepted Answer

A)   Alu in Homo sapiens
B)   P elements in Drosophila
C)   Mu in bacteria
D)   Ty in yeast
E)   All of the answers are correctF) A) and E)
G) B) and E)

Question 11

Which of the following may account for the process of gene conversion?

Accepted Answer

A)   DNA mismatch repair
B)   DNA gap repair
C)   Photolyase activity
D)   Nucleotide excision repair
E)   More than one of the aboveF) All of the above
G) C) and E)

Question 12

The Holliday model is used to explain which of the following?

Accepted Answer

A)   Recombination between homologous chromosomes
B)   Recombination between sister chromatids
C)   The creation of harlequin chromosomes
D)   The action of transposons
E)   None of the answers are correctF) A) and C)
G) A) and D)

Question 13

The type of transposition in which the number of transposons increases in the genome is called .

Accepted Answer

A)   Replicative transposition
B)   Simple transposition
C)   Site-specific transposition
D)   Complex transpositionE) None of the above
F) C) and D)

Question 14

Site-specific recombination occurs between homologous sequences of DNA.
FALSE

Accepted Answer

A) True 
 B)False  False

Question 15

A heteroduplex is a DNA double helix that contains mismatches.

Accepted Answer

A) True 
 B)False

Question 16

LINEs and SINEs may be due to high levels of transposable element activity.

Accepted Answer

A) True 
 B)False

Question 17

Transposon tagging may be used for which of the following reasons?

Accepted Answer

A)   To test if a transposon is replicative
B)   As a tool to clone novel genes
C)   To track the movement of transposons between species
D)   To inactivate transposons in a genomeE) All of the above
F) A) and B)

Question 18

Alu is an example of a retro element in the human genome.

Accepted Answer

A) True 
 B)False

Question 19

Which enzyme is unique to the retro elements?

Accepted Answer

A)   Reverse transcriptase
B)   Reverse resolvase
C)   Transposase
D)   Integrase
E)   Reverse integraseF) None of the above
G) A) and B)

Question 20

Long-terminal repeats are unique to which group of transposons?

Accepted Answer

A)   Composite transposon
B)   Non-viral retro element
C)   Viral-like retro element
D)   Replicative transposon
E)   Insertion sequenceF) A) and B)
G) A) and C)

Exam 17: Recombination and Transposition at the Molecular

Chromosomes that are genetically the same, but have different banding patterns using Hoechst 33258 and Giemsa stains, are called giemequin chromosomes.

Correct AnswerverifiedFalse

A incomplete transposon contains all of the information necessary to conduct transposition.

Correct AnswerverifiedShow Answer

In the Perry-Wolff experiments with harlequin chromosomes, colcemid was applied to the cells following labeling with BrdU for what reason?

Correct AnswerverifiedShow Answer

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Correct AnswerverifiedShow Answer

Which of the following is technically not part of the genetic information of a transposable element?

Correct AnswerverifiedShow Answer

Transposable elements in bacteria are commonly called insertion sequences.

Correct AnswerverifiedTrue

The process of recombination occurs during metaphase I of meiosis.

Correct AnswerverifiedShow Answer

Bacteriophage l inserts into a bacterial chromosome using which of the following?

Correct AnswerverifiedShow Answer

Which of the following domain types is unique to the heavy chain of the polypeptide?

Correct AnswerverifiedShow Answer

Which of the following is an example of a transposable element?

Correct AnswerverifiedShow Answer

Which of the following may account for the process of gene conversion?

Correct AnswerverifiedShow Answer

The Holliday model is used to explain which of the following?

Correct AnswerverifiedShow Answer

The type of transposition in which the number of transposons increases in the genome is called .

Correct AnswerverifiedShow Answer

Site-specific recombination occurs between homologous sequences of DNA. FALSE

Correct AnswerverifiedFalse

A heteroduplex is a DNA double helix that contains mismatches.

Correct AnswerverifiedShow Answer

LINEs and SINEs may be due to high levels of transposable element activity.

Correct AnswerverifiedShow Answer

Transposon tagging may be used for which of the following reasons?

Correct AnswerverifiedShow Answer

Alu is an example of a retro element in the human genome.

Correct AnswerverifiedShow Answer

Which enzyme is unique to the retro elements?

Correct AnswerverifiedShow Answer

Long-terminal repeats are unique to which group of transposons?

Correct AnswerverifiedShow Answer

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