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What advantage do phosphodiesters have compared to other esters?

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The negative charge serves to repel nucleophilic species such as OH-. Thus, the phosphodiester linkage is more stable because it is more resistant to hydrolytic cleavage.

Which molecules that are produced during transcription carry information for use as a template during translation?


A) mRNA
B) tRNA
C) rRNA
D) snRNA
E) DNA

F) A) and C)
G) C) and D)

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Each three-base codon encodes a specific _____.


A) DNA nucleotide
B) mRNA nucleotide
C) tRNA nucleotide
D) rRNA nucleotide
E) amino acid

F) B) and D)
G) A) and C)

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A noncoding region within a gene is known as a _____.


A) intron
B) exon
C) missense region
D) split gene
E) None of the answers is correct.

F) B) and D)
G) A) and B)

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A

The flow of genetic information from DNA to protein is called _____.


A) replication
B) transcription
C) translation
D) gene expression
E) All of the answers are correct.

F) A) and D)
G) A) and C)

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Each amino acid residue in a protein is encoded by a set of three bases in an mRNA referred to collectively as a(n) __________________.

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The genetic code is not universal. Where are exceptions found?

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Exceptions are found in severa...

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Draw how the dNTP is added to a DNA strand at the 3' end.

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The drawing should indicate cl...

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Briefly describe the Meselson and Stahl experiment that indicated that DNA replication is semiconservative.

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Meselson and Stahl grew bacteria in the presence of 15N, or "heavy" nitrogen. They rapidly replaced the 15N media with 14N, or light nitrogen. DNA was extracted at various time intervals during the growth of the bacteria, representing different stages of replication (generations). They examined the DNA using density-gradient equilibrium sedimentation and observed that no "heavy" DNA was present in the first generation but that the DNA was intermediate between light and heavy. After the second generation, there were equal amounts of intermediate and light. This confirmed that one strand of the parent DNA is present in each daughter strand of replicated DNA.

What is an advantage of codon degeneracy?

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Changes in the third position often have...

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Describe the DNA helix proposed by Watson and Crick.

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The DNA model proposed by Watson and Cri...

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The technique(s) used by Franklin and Wilkins to deduce the structure of DNA was


A) absorbance spectrophotometry.
B) electron microscopy.
C) x-ray diffraction.
D) All of the answers are correct.
E) None of the answers is correct.

F) None of the above
G) A) and D)

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In bacterial mRNA, the initiating AUG codon is preceded several nucleotides away by a purine-rich sequence called the __________________ , which base-pairs with a complementary sequence in an rRNA.

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Shine-Dalg...

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Draw two nucleotides in DNA showing the linkage between the sugars.

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blured image The 3' oxygen of one nucleotide is link...

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__________________ is the most abundant type of RNA in a cell.

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Ribosomal ...

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Which of the following is correct concerning the adaptor molecule tRNA?


A) tRNA contains an anticodon sequence that serves as the template recognition site.
B) The amino acid is attached to the 5' end of tRNA.
C) tRNA contains a poly A tail at the 3' end.
D) tRNA is the largest RNA in the cell.
E) tRNA serves as the gene in some viruses.

F) C) and D)
G) A) and D)

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In an amino acyl-tRNA, the amino acid is attached to the CCA sequence at the _________ end of the tRNA.

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The enzyme that is capable of synthesizing DNA from an RNA template is __________________.

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reverse tr...

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The advantage(s) to having most genes of higher eukaryotes, such as birds and mammals, be split include


A) the potential for generating related proteins.
B) the preservation of functional units (e.g. catalytic site) .
C) the resistance to mutation.
D) the potential for generating related proteins and the preservation of functional units (e.g. catalytic site) .
E) None of the answers is correct.

F) B) and D)
G) None of the above

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What are two features of mature eukaryotic mRNA that are unique as compared to prokaryotic mRNA?

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Eukaryotic mRNA has ...

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