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Each of these statements is True EXCEPT one.Identify the exception.


A) Monoamine oxidase is the main enzyme responsible for the degradation of catecholamines.
B) β₁ receptors respond equally well to both epinephrine and norepinephrine.
C) β₂ receptors are not innervated by sympathetic neurons, so are more sensitive to epinephrine, delivered via the blood.
D) Activation of α receptors opens Na⁺ channels in the membrane.

E) All of the above
F) None of the above

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Describe the different types of adrenergic receptors in the autonomic nervous system.Which neurotransmitter binds to each type? For those that bind more than one neurotransmitter, how does the response to the neurotransmitters compare?

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Alpha 1, alpha 2, beta 1, beta 2, and be...

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Match the answers to the questions. -The neural pathway from the spinal cord to the target tissue has two neurons, the preganglionic neuron and the postganglionic neuron.


A) True only for the sympathetic division
B) True only for the parasympathetic division
C) True for both divisions

D) None of the above
E) All of the above

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What steps are necessary to terminate neurotransmitter action? What would happen if these steps failed?

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Neurotransmitter molecules are either en...

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Increased parasympathetic stimulation


A) increases heart rate.
B) increases gastric motility.
C) causes sweat glands to release sweat.
D) causes blood vessels in the skin to dilate.
E) causes the pupils to dilate.

F) C) and E)
G) C) and D)

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Match the response with the type of chemical. -salivation


A) sympathetic agonist
B) parasympathetic agonist

C) A) and B)
D) undefined

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Epinephrine and norepinephrine that are released from the adrenal glands affect target tissue for a longer period of time than the same substances released from neurons at their peripheral receptors.Why?


A) The adrenal gland releases larger amounts of the neurotransmitters than the neurons.
B) The hormones released from the adrenal glands bind to different receptors than those released from neurons.
C) There are no enzymes to break down epinephrine and norepinephrine in the blood and very little in peripheral tissues.
D) The effectors are less sensitive to epinephrine and norepinephrine released by the adrenal glands.
E) The epinephrine and norepinephrine from the adrenal glands are released by sympathetic neurons, whereas parasympathetic neurons release these substances at the effector organs.

F) C) and D)
G) A) and D)

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Match the response with the type of chemical. -pupil dilation


A) sympathetic agonist
B) parasympathetic agonist

C) A) and B)
D) undefined

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If humans administered a physiological dose of ufo-epi responded to the chemical, which of the following would indicate ufo-epi is an epinephrine agonist?


A) constriction of respiratory tubes
B) hyperglycemia (high blood glucose)
C) increase in fatty acids in the blood
D) localized sweating
E) decreased heart rate

F) B) and E)
G) D) and E)

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The adrenal medulla is important to the sympathetic branch of the autonomic nervous system because


A) it is a source of catecholamines.
B) it is considered a modified sympathetic ganglion.
C) it releases epinephrine and norepinephrine directly into the blood.
D) it is a source of catecholamines and it is considered a modified sympathetic ganglion.
E) it is a source of catecholamines, it is considered a modified sympathetic ganglion, and it releases epinephrine and norepinephrine directly into the blood.

F) A) and C)
G) A) and E)

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Match the following with its description. -released by all autonomic preganglionic neurons


A) acetylcholine
B) norepinephrine
C) cholinergic nicotinic receptor
D) adrenergic receptor
E) cholinergic muscarinic receptor

F) A) and D)
G) None of the above

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The signal molecule ________ elicits the stronger response from alpha receptors.

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The presence of two peripheral efferent neurons in a pathway is typical of the ________ division.


A) somatic
B) sensory
C) autonomic
D) somatic and sensory
E) somatic and autonomic

F) A) and B)
G) C) and E)

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Both alpha-bungarotoxin and curare bind to the same neurotransmitter receptor, but only curare binds reversibly.Which receptor is involved? List some locations for this receptor.Would either toxin be appropriate to use as a paralytic during surgery? Explain your answer.Are all such receptors necessarily affected by a given toxin in the same way? Explain the significance of your answer.

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Both of these toxins bind to the nicotin...

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Describe the different types of cholinergic receptors in the nervous system.Which neurotransmitter binds to each type?

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Cholinergic receptors are eith...

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You and your fellow deep-sea scientists have discovered a new form of marine invertebrate, and are anxious to determine the similarities and differences to animals already characterized.Chemical analysis reveals the following concentrations of permeable cations:  [on  in] mM out] mMNa+50450K+42020Mg++1060Cl50550\begin{array} { | l | l | l | } \hline \text { [on } & \text { in] } \mathrm { mM } & \text { out] } \mathrm { mM } \\\hline \mathrm { Na } ^ { + } & 50 & 450 \\\hline \mathrm { K } ^ { + } & 420 & 20 \\\hline \mathrm { Mg } ^ { + + } & 10 & 60 \\\hline \mathrm { Cl } ^ { - } & 50 & 550 \\\hline\end{array} Nernst equation: Eion = 61/z × log [ion]out/[ion]in -Control of the neuromuscular junction in this new invertebrate is found to involve dual innervation, where one motor neuron secretes an excitatory neurotransmitter and another secretes an inhibitory neurotransmitter onto the muscle.How does this compare to the human neuromuscular junction? Propose three different types of inhibitory receptors/channels that would produce inhibition of the invertebrate muscle, specifying ion and direction of ion flow.For each ion, calculate the equilibrium potential.What similarity do you notice in the equilibrium potentials of the ions involved, and how is that significant? How may inhibition be accomplished in human muscle?

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The human neuromuscular junction is inne...

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Sweat glands contain


A) cholinergic receptors.
B) alpha receptors.
C) beta receptors.
D) All of the answers are correct.
E) None of the answers are correct.

F) C) and D)
G) A) and C)

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Antagonistic control of efferent output is typical of the ________ division.


A) somatic
B) sensory
C) autonomic
D) somatic and sensory
E) somatic and autonomic

F) D) and E)
G) A) and D)

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