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Two people (both heterozygotes) are able to taste a chemical substance called PTC. The ability to taste PTC is caused by a dominant allele (T) . The inability to taste PTC is caused by a recessive allele (t) . What proportion of their children would be expected not to be able to taste PTC?


A) 3/4
B) All
C) 1/4
D) 2/3
E) none

F) All of the above
G) A) and D)

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In regions where malaria is present, it acts as a selective agent that favors the heterozygous phenotype, because people with sickle-cell trait produce more offspring than those with only normal hemoglobin, who may die of malaria.

A) True
B) False

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What produces new alleles at a locus?


A) natural selection
B) recombination
C) mutation
D) migration
E) genetic drift

F) A) and B)
G) A) and E)

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Which statement concerning polygenic traits is not true?


A) They are governed by more than one genetic locus.
B) Their expression is often influenced by genetic/environmental interactions.
C) The alleles have an additive effect on the phenotype.
D) They are continuous traits
E) The most frequently discussed are skin, hair and eye color.

F) B) and D)
G) B) and C)

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The ABO blood type system consists of ______ alleles.


A) 6
B) 4
C) 3
D) 2
E) 5

F) B) and C)
G) A) and E)

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Gregor Mendel is known for which of the following?


A) He developed theories of evolutionary change.
B) He discovered the structure of the DNA molecule.
C) He studied characteristics that are influenced by several genetic loci.
D) He discovered the fundamental principles of how traits are inherited.
E) He developed the theory of inheritance of acquired characteristics.

F) C) and D)
G) None of the above

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Which of the following is not a polygenic trait?


A) stature
B) skin color
C) eye color
D) ABO blood type
E) hair color

F) C) and E)
G) A) and C)

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What is an individual's actual genetic make-up called?


A) phenotype
B) homozygosity
C) recessiveness
D) phenotypic ratio
E) genotype

F) A) and B)
G) B) and E)

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What is meant by the statement, "natural selection is the one factor that can cause directional change in allele frequency relative to specific environmental factors"?

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The statement "natural selection is the ...

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The relationship between malaria and the HbS allele is an example of natural selection as a factor that can cause directional change in allele frequencies.

A) True
B) False

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In Mendel's experiments, the tall parental (P) plants


A) were homozygous for the allele for tallness
B) were heterozygous at the locus controlling height
C) could NOT be crossed with short plants
D) were homozygous for the allele for shortness
E) were heterozygous for the allele for shortness

F) B) and C)
G) C) and D)

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In Mendel's experiments, what was the ratio of tall to short plants in the F2 generation?


A) 15 to 1
B) 3 to 1
C) ½ tall, ½ short
D) 4 to 1
E) 5 to 1

F) C) and D)
G) B) and E)

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New alleles are the results of mutations.

A) True
B) False

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In order for a mutation to be passed on to offspring, the mutation must


A) occur in a gamete
B) be beneficial
C) occur in a somatic cell
D) result in additional chromosomes
E) have negative evolutionary consequences

F) A) and B)
G) D) and E)

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Define genetic drift. How are founder effect and genetic drift related?

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Genetic drift is a mechanism of evolutio...

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All human genetic disorders are inherited as recessive traits.

A) True
B) False

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Discuss the differences between Mendelian and polygenic modes of inheritance. Provide an example of a Mendelian and a polygenic trait.

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Mendelian inheritance and polygenic inhe...

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Explain Mendel's principle of segregation.

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Mendel's principle of segregation states...

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Mitochondrial DNA (mtDNA) is extremely useful for studying genetic change over time.

A) True
B) False

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Genetic drift is


A) the change in allele frequencies produced by random factors
B) the result of large populations
C) the opposite of founder effect
D) not evolutionary change
E) the change in allele frequencies produced by nonrandom factors

F) B) and D)
G) B) and E)

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