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Suppose we applied a drug to a neuron that caused its sodium gates to suddenly open wide. What would happen?


A) hyperpolarization of the membrane
B) an increase in the threshold
C) an action potential
D) nothing, because potassium gates would compensate

E) B) and C)
F) A) and D)

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One disadvantage of the blood-brain barrier is that it keeps out most forms of nutrition.

A) True
B) False

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What is the difference in voltage called that typically exists between the inside and the outside of a neuron?


A) concentration gradient
B) generator potential
C) resting potential
D) shock value

E) None of the above
F) B) and C)

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Axons are covered with an insulating material called a myelin sheath.

A) True
B) False

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Protein channels allow ____ to cross the cell membrane.


A) large charged molecules
B) small charged molecules
C) large uncharged molecules
D) small uncharged molecules

E) A) and B)
F) All of the above

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When the neuron is at rest, what is responsible for moving potassium ions OUT of the cell?


A) a concentration gradient
B) an electrical gradient
C) both a concentration gradient and an electrical gradient
D) the sodium-potassium pump

E) B) and D)
F) B) and C)

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Who was the first researcher to demonstrate that neurons are separate from one another?


A) Curt P. Richter
B) Santiago Ramon y Cajal
C) Charles S. Sherrington
D) Jose Delgado

E) A) and B)
F) A) and C)

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Dendrites contain the nuclei, ribosomes, mitochondria, and other structures found in most cells.

A) True
B) False

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When the neuron is at rest, what is responsible for moving potassium ions into the cell?


A) concentration gradient
B) an electrical gradient
C) the sodium-potassium pump
D) both the sodium-potassium pump and electrical gradient

E) All of the above
F) C) and D)

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If the brain does not have enough thiamine, what is it unable to do?


A) maintain its blood-brain barrier
B) pump glucose across the blood-brain barrier
C) produce certain neurotransmitters
D) metabolize glucose

E) A) and D)
F) A) and B)

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Myelin covers:


A) all axons
B) most dendrites
C) some axons in vertebrates and none in invertebrates
D) all vertebrate axons and some invertebrate axons

E) A) and C)
F) A) and D)

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A greater amount of branching on dendrites allows them to:


A) manufacture more mitochondria.
B) have a larger surface area available for receiving information from other neurons.
C) increase their membrane permeability.
D) lower their resting potential.

E) None of the above
F) All of the above

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Which of the following would produce a hyperpolarization of a neuron?


A) applying a negative charge inside the neuron with a microelectrode
B) applying a positive charge inside the neuron with a microelectrode
C) increasing the membrane's permeability to sodium
D) decreasing the membrane's permeability to potassium

E) None of the above
F) A) and B)

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When the neuronal membrane is at rest, the sodium channels:


A) permit sodium ions to pass quickly and easily.
B) permit potassium ions to cross instead of sodium.
C) are closed.
D) fluctuate rapidly between open and closed.

E) None of the above
F) A) and B)

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Which of the following is an important function of the blood-brain barrier?


A) It enables more nutrients to reach the brain.
B) It maintains an electrical gradient.
C) It aids in the production of neurotransmitters.
D) It protects the brain from most viruses.

E) B) and D)
F) A) and D)

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Stimulation of a neuron beyond a certain level is called the:


A) firing threshold
B) hillock threshold
C) threshold of excitation
D) threshold of inhibition

E) C) and D)
F) B) and D)

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What is one major cause for the resting potential of a neuron's membrane?


A) a difference in size between axons and dendrites
B) a high permeability of the membrane to water molecules
C) the refractory period of the membrane
D) the sodium-potassium pump

E) A) and B)
F) A) and C)

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Which two factors affect the speed of an action potential?


A) the strength and frequency of the stimulus
B) the location of the cell body and the length of the axon
C) the length and diameter of the axon
D) the presence of myelin and the diameter of the axon

E) A) and B)
F) C) and D)

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Which of the following is NOT true of astrocytes?


A) They wrap around the presynaptic terminals of several axons.
B) They help synchronize the activity of the axons.
C) They remove waste material.
D) They make up the myelin sheaths in the periphery of the body.

E) None of the above
F) All of the above

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Which of the following is an advantage of having a resting potential?


A) The toxic effects of sodium are minimized inside the cell.
B) No energy is required to maintain it.
C) The cell is prepared to respond quickly to a stimulus.
D) All of the ions are maintained in equal concentrations throughout the cytoplasm.

E) A) and B)
F) None of the above

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