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Which type of mutation could have the biggest evolutionary consequence?


A) A mutation in a lung cell
B) A mutation in a kidney cell
C) A mutation in a stomach cell
D) A mutation in a germ-line cell

E) None of the above
F) A) and C)

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Based on which of the following pieces of evidence about the transforming agent did Avery conclude that DNA is the hereditary material?


A) The transforming material had the same elements as DNA.
B) The transforming material was not destroyed by protein-digesting enzymes.
C) The transforming material was destroyed by DNA-digesting enzymes.
D) All of the choices are correct.

E) A) and B)
F) None of the above

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A change in the genetic message is called a ____________.

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mutation

When Frederick Griffith infected mice with S.pneumoniae that lacked a capsule,the mice


A) remained healthy.
B) died of blood poisoning.
C) became ill but lived.
D) reproduced quicker.

E) A) and B)
F) A) and C)

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When Griffith injected a mixture of dead S bacteria and live,capsuleless R bacteria,the mice


A) remained healthy.
B) died of blood poisoning.
C) became ill but lived.
D) reproduced quicker.

E) B) and C)
F) C) and D)

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The Hershey-Chase experiment demonstrated that protein,not DNA,is the hereditary material.

A) True
B) False

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Meselson and Stahl proved that


A) DNA is the genetic material.
B) DNA is made from nucleotides.
C) DNA replicates in a semiconservative manner.
D) DNA contains nitrogen.

E) A) and B)
F) B) and C)

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The significance of the Griffith,Avery,and Hershey-Chase experiments was that they demonstrated that


A) genes were located on chromosomes.
B) enzymes transformed bacteria.
C) proteins were what genes were composed of.
D) DNA was the molecule of heredity.

E) A) and D)
F) None of the above

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The structure of DNA is called a


A) alpha helix.
B) beta helix.
C) double helix.
D) triple helix.

E) All of the above
F) B) and C)

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C

A base substitution will lead to a frame-shift mutation.

A) True
B) False

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The building blocks of DNA are called


A) proteins.
B) bases.
C) nucleotides.
D) acids.

E) None of the above
F) All of the above

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If an error is made during DNA replication,mechanisms of DNA repair always correct the mistakes.

A) True
B) False

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All of the following can cause mutation except


A) UV light.
B) mistakes in DNA replication.
C) centrifuging.
D) cigarette smoke.
E) toxic chemicals.

F) A) and B)
G) A) and D)

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Why are deletions or insertions of nucleotides likely to be more detrimental than base substitutions?

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All of the following are correct about DNA replication except


A) DNA polymerase is the enzyme that adds nucleotides to one another.
B) DNA polymerase can only synthesize DNA in the 5' to 3' direction.
C) Helicase is the enzyme which rewinds the DNA after replication is finished.
D) DNA polymerase can only add nucleotides to an existing strand.
E) The lagging strand has many primers.

F) All of the above
G) B) and E)

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Which scientists' work first suggested that DNA had the shape of a helix?


A) Wilkins and Franklin
B) Watson and Crick
C) Hershey and Chase
D) Avery,Macleod,and McCarty
E) Campbell and Wilmut

F) B) and E)
G) C) and D)

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A

When Frederick Griffith infected mice with a virulent strain of Streptococcus pneumonia,the mice


A) remained healthy.
B) died of blood poisoning.
C) became ill but lived.
D) reproduced quicker.

E) A) and B)
F) A) and C)

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Which choice describes how the DNA molecule replicates?


A) Semiconservative
B) Dispersive
C) Conservative
D) Either dispersive or semiconservative depending on the pH
E) Either dispersive or conservative depending on the organism.

F) None of the above
G) D) and E)

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Hershey and Chase tagged the DNA of viruses with radioactive phosphorus,and their protein coats with radioactive sulfur.When the viruses were allowed to infect bacteria,what did the viruses transfer to the bacteria?


A) Radioactive phosphorus and sulfur
B) Radioactive sulfur
C) DNA
D) Protein

E) C) and D)
F) A) and C)

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All of the following are correct about mutations except


A) without mutations,there would be no variation and no evolution.
B) mutations change the bases in DNA.
C) a mutation in a somatic cell will be passed on to subsequent generations.
D) some mutations change the nucleotide sequence of a gene.
E) some mutations remove nucleotides from a gene.

F) B) and C)
G) A) and E)

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