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Which of the statements below is false regarding the relationship between malaria and the HbS allele?


A) There is no geographic correlation between the distribution of the HbS allele and malaria.
B) Heterozygotes have greater resistance to malaria than homozygous individuals.
C) The malarial parasite does not reproduce very well in the red blood cells of heterozygotes.
D) Malaria is caused by the Plasmodium parasite.
E) Most people are homozygous for the HbA allele.

F) D) and E)
G) All of the above

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Mitochondrial DNA mtDNA) is extremely useful for studying genetic change over time.

A) True
B) False

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The HbS allele increased in frequency in West African populations due to which of the following?


A) sickle-cell anemia
B) genetic drift
C) migration
D) increased mutation rates
E) natural selection

F) A) and B)
G) C) and E)

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What is an individual's actual genetic make-up called?


A) phenotype
B) homozygosity
C) recessiveness
D) phenotypic ratio
E) genotype

F) B) and D)
G) A) and D)

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Explain the concepts of dominance, co-dominance, and recessiveness as used in modern genetics.

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At a hypothetical locus, a man's genotype is Aa. What proportion of his gametes would be expected to receive the A allele?


A) All
B) Β½
C) ΒΎ
D) ΒΌ
E) None

F) B) and D)
G) All of the above

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Evolution can be most succinctly defined as


A) the appearance of new species
B) the change from one species to another in one generation
C) the change in allele frequency from one generation to the next
D) any type of genetic mutation
E) genetic drift

F) C) and E)
G) None of the above

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Explain how two parents who do NOT express a particular trait in their phenotype can nevertheless produce children who express the trait. Give an example of a specific trait or disease where this could occur.

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This phenomenon can occur when both pare...

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The ABO blood type system consists of ______ alleles.


A) 6
B) 4
C) 3
D) 2
E) 5

F) B) and D)
G) D) and E)

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Gregor Mendel


A) published his results and won the Nobel Prize for his discoveries
B) was trained as a geneticist
C) did not know about chromosomes
D) was a professor at the University of Vienna
E) never published his work

F) A) and D)
G) A) and C)

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Discuss the differences between Mendelian and polygenic modes of inheritance. Provide an example of a Mendelian and a polygenic trait.

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Mendelian inheritance and polygenic inhe...

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Evolution can be described as a two-stage process that includes which of the following?


A) genetic drift followed by migration
B) natural selection followed by migration
C) recombination followed by mutation
D) production of variation followed by natural selection acting on this variation
E) production and distribution of variation

F) All of the above
G) B) and C)

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What is meant by the statement, "natural selection is the one factor that can cause directional change in allele frequency relative to specific environmental factors"?

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The statement "natural selection is the ...

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Explain Mendel's principle of independent assortment.

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Mendel's principle of independent assort...

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Polygenic traits


A) are discrete
B) have a continuous range of expression
C) are controlled by only one genetic locus
D) include the ABO blood type system and cystic fibrosis
E) are also called Mendelian traits

F) A) and E)
G) D) and E)

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Which statement concerning polygenic traits is not true?


A) They are governed by more than one genetic locus.
B) Their expression is often influenced by genetic/environmental interactions.
C) The alleles have an additive effect on the phenotype.
D) They are continuous traits
E) The most frequently discussed are skin, hair and eye color.

F) C) and D)
G) All of the above

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In a hypothetical situation, B is the allele that causes brachydactyly. If a man who has normal fingers bb) and a woman with brachydactyly Bb) have children, what proportion of these children would you expect to have normal fingers? Hint: Use a Punnett square) .


A) None
B) All
C) 1/4
D) 3/4
E) 1/2

F) A) and E)
G) None of the above

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Which of the following is not a polygenic trait?


A) stature
B) skin color
C) eye color
D) ABO blood type
E) hair color

F) B) and D)
G) B) and C)

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In order for a mutation to be passed on to offspring, the mutation must


A) occur in a gamete
B) be beneficial
C) occur in a somatic cell
D) result in additional chromosomes
E) have negative evolutionary consequences

F) A) and E)
G) C) and D)

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What is it called when a person possesses two different alleles at the same locus, and both alleles are expressed in the phenotype?


A) recessiveness
B) codominance
C) dominance
D) homozygosity
E) X-linkage

F) B) and D)
G) B) and E)

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